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Paul A McEwan Selected Research

Interleukin-2 (IL2)

5/2015Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo.
7/2014Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors.

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Paul A McEwan Research Topics

Disease

3Asthma (Bronchial Asthma)
12/2016 - 07/2014
2Thrombosis (Thrombus)
04/2010 - 11/2009
1Pulmonary Arterial Hypertension
01/2023
1Angioedema
10/2022
1Hereditary Angioedemas
10/2022
1Hemorrhage
04/2010
1Tuberculosis (Tuberculoses)
12/2006

Drug/Important Bio-Agent (IBA)

3emt protein-tyrosine kinase (IL2-inducible T-cell kinase)IBA
12/2016 - 07/2014
2EnzymesIBA
10/2022 - 04/2010
2Interleukin-2 (IL2)IBA
05/2015 - 07/2014
2T-Cell Antigen Receptors (T-Cell Receptor)IBA
05/2015 - 07/2014
1Cyclic GMP-Dependent Protein Kinase Type IIBA
01/2023
1sebetralstatIBA
10/2022
1BradykininIBA
10/2022
1Plasma KallikreinIBA
10/2022
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2016
1Tyrosine (L-Tyrosine)FDA Link
07/2014
1Phosphotransferases (Kinase)IBA
07/2014
1Factor IX (Coagulation Factor IX)FDA LinkGeneric
04/2010
1Factor XI (Plasma Thromboplastin Antecedent)IBA
04/2010
1Enzyme Precursors (Zymogens)IBA
04/2010
1Platelet Membrane GlycoproteinsIBA
11/2009
1von Willebrand FactorIBA
11/2009
1NitrogenIBA
12/2006
1ThioredoxinsIBA
12/2006
1Oxygen (Dioxygen)IBA
12/2006